New NICE guidance: genetic testing now recommended before Clopidogrel
New NICE guidance: genetic testing now recommended before Clopidogrel
FOR GPS, CONSULTANTS, PHARMACISTS AND CLINICS
State-of-the-art DNA testing and the latest pharmacogenomic evidence to support your prescribing decisions: fewer adverse reactions, more personalised prescribing and a new service line for your practice.
Registered with the MHRA · members of BIVDA, CERSI-PGx and the IPN
CE & UKCA marked
UPGx protocol · The Lancet
DPWG-actionable only
AWARD-WINNING · EVIDENCE AND RECOGNITION
BY ROLE
Start with your role. Each area brings together the evidence, guidance and articles most relevant to you, and we’ll add more specialties over time.
GPs
Help patients find the right medication, at the right dose, the first time. Guidance on repeat prescribing, long-term conditions and when to test.
A new paid service for your pharmacy. Medicines optimisation and pharmacogenomics in the community, with clear, actionable recommendations.
Offer your patients the most advanced prescribing support in your specialty: Clopidogrel and cardiovascular medicines, mental health medicines and more.
Cardiology & stroke
Psychiatry
Gastroenterology
More coming soon
THE SCIENCE BEHIND OUR TEST
Every Mantara report follows guidance from leading pharmacogenomic experts across the UK and Europe, using the same protocol and recommendations as the UPGx study published in The Lancet (2023).
Partner laboratory in Germany with validated, high-precision genotyping.
CE and UKCA-marked software from bio.logis, accredited by the College of American Pathologists.
DPWG recommendations and PREPARE findings. No “informational” results.
Published in The Lancet, 2023. Led by European experts including the NHS Chair of Pharmacogenetics at the University of Liverpool.
6,930
patients across 7 European countries, including the UK
30%
fewer serious side effects with genotype-guided prescribing
12
genes in the panel we follow
78
medicines with DPWG-actionable advice
PARTNER WITH MANTARA
Stock kits at consumable cost and only pay for laboratory analysis when a sample is registered.
STOCK KITS
Covers consumables and tracked postage. Keep kits on the shelf for patients who want to test today.
Barcoded kits added to your stock
Automatic reorder when you run low
PAY AS YOU TEST
The laboratory analysis is invoiced monthly, only for samples your patients register.
One automatic PDF invoice a month
Remaining £274 only payable on registration
PARTNER PORTAL
See which kits are with patients, at the lab or reported, and share reports securely.
Track status in real time
Order kits in bulk
GETTING STARTED
01
DAY 1
We learn about your practice and patients.
02
DAY 2
GMC, NMC or GPhC check and your partner account.
03
DAY 3
Starter stock dispatched the same day.
04
ONGOING
Patients test; you follow every sample in the portal.
RAPID CYP2C19 TESTING
Around 32% of UK patients may not metabolise Clopidogrel effectively, rising to 57% in British South Asian populations.Source: NICE diagnostics guidance DG59, CYP2C19 genotype testing before Clopidogrel (2024).
FAST TURNAROUND
Lab-based rapid CYP2C19 test for timely prescribing decisions.
BEYOND NICE CRITERIA
Offer testing after a previous stroke, heart attack, stent or clot diagnosis.
WIDER INSIGHT
Add the PGx Panel Test covering 78 medicines when it helps your patient.
ONGOING SUPPORT
You won’t be doing this alone. From your very first PGx patient, our clinical and marketing teams help you introduce PGx testing, interpret results and grow demand.
Our clinical team is on hand for you and your patients, from the first conversation to the report review.
Onboarding call and CPD-style clinician guide
Help interpreting any report, by phone or email, within one working day
Evidence pack for pre-authorisation, audits and appraisals
We help you build demand so the service pays for itself.
Patient leaflets, posters and consult-room cards, co-branded
Website, email and social copy you can reuse
A listing in the Mantara partner finder, with your clinic details
PRIVATE MEDICAL INSURANCE
Both Mantara tests have their own CCSD codes, so you can bill them to your patients’ private medical insurers in the same way as other diagnostic tests.
CCSD CODES
PGx Panel Test (12 genes, 78 medicines)
3028G
Rapid Clopidogrel (CYP2C19) Test
3033G
How it works
• Check the patient’s cover. The patient or your practice confirms with their insurer that the test is covered under their policy.
• Get pre-authorisation. Quote the CCSD code and the clinical reason for testing (e.g. starting Clopidogrel after a stroke, or a history of side effects).
• Order and bill as usual. Order through your partner account and invoice the insurer using the code.
Our team can provide supporting evidence for pre-authorisation, including the NICE recommendation for CYP2C19 testing in stroke and TIA patients.
PARTNER CLINICIANS
Testimonials and partner logos to be supplied by Mantara. Placeholders shown so the layout is agreed before go-live.
“Clinician testimonial 1 — to be supplied. Two or three sentences on how PGx testing changed prescribing in the practice.”
[Name, role]
[Practice or clinic, town]
“Clinician testimonial 2 — to be supplied. Two or three sentences on how PGx testing changed prescribing in the practice.”
[Name, role]
[Practice or clinic, town]
“Clinician testimonial 3 — to be supplied. Two or three sentences on how PGx testing changed prescribing in the practice.”
[Name, role]
[Practice or clinic, town]
Partner logo
Partner logo
Partner logo
Partner logo
Partner logo
PARTNER ENQUIRY
Tell us about your practice and we’ll call to discuss the right package, bulk pricing and training.
020 3818 5875
Monday to Friday
info@mantara.co
We reply within one working day
Clinician guide (PDF)
Evidence summary and how to read a report
1
Who is ordering
2
Verify
3
Next steps
The rapid Clopidogrel test uses a cheek swab that must be taken by a healthcare professional. Tell us who you are and we’ll guide you.
I’m a healthcare professional
Doctor, nurse or pharmacist ordering for a patient or for my clinic.
I’m a patient, or ordering for a family member
We’ll help you get the swab taken, or suggest the panel test you can order online today.
Why we ask: the swab must be taken by a registered healthcare professional to meet the test’s instructions for use.
Who is ordering
2
Verify
3
Next steps
We check registration numbers against the public register before your first dispatch. You only do this once.
Rapid Clopidogrel test (CYP2C19)
Results within days · for 1 patient
Who is ordering
2
Your options
3
Next steps
This test needs a healthcare professional to take the cheek swab. Choose what suits you:
Connect me with a partner clinician
We introduce you to a Mantara partner near you who can take the swab.
Most popular
My GP, nurse or pharmacist can take it
We email them a referral link so they can order it for you.
Want answers sooner?
Saliva sample at home, no referral needed. Order online today.
Who is ordering
2
Your options
3
Next steps
This test needs a healthcare professional to take the cheek swab. Choose what suits you:
Connect me with a partner clinician
We introduce you to a Mantara partner near you who can take the swab.
Most popular
My GP, nurse or pharmacist can take it
We email them a referral link so they can order it for you.
Want answers sooner?
Saliva sample at home, no referral needed. Order online today.
Who is ordering
2
Your options
3
Next steps
Request sent
Request sent
2
A partner clinician contacts you
Within 2 working days, by phone or email
3
They take the cheek swab
In clinic — rapid results within days
4
Your clinician explains the result
And prescribes the right anti-platelet medication for you
Want answers sooner?
Saliva sample at home, no referral needed. Order online today.
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