THE NHS 10-YEAR PLAN: WHAT IT MEANS FOR PHARMACOGENOMICS
The NHS 10-Year Health Plan for England, Fit for the Future, outlines a bold vision to transform healthcare delivery, improve outcomes, and tackle inequalities by 2035. A key theme of the plan is delivering care that is “proactive, predictive, personalised and preventative.” This ambition has significant implications for the future of Pharmacogenomics (PGx).
A Shift to Personalised, Preventative Care
The plan commits to harnessing cutting-edge technologies — including genomics and digital innovation — to reshape how care is delivered. Pharmacogenomics, which uses genetic insights to tailor medication choices, is central to this evolution. It enables clinicians to:
Avoid trial-and-error prescribing
Reduce adverse drug reactions
Improve response rates in conditions like depression, cardiovascular disease, cancer, and chronic pain
These outcomes directly support the plan’s goal of ensuring that “the right care is delivered at the right time to every individual.”
Tackling Inequalities with Smarter Prescribing
The 10-Year Plan repeatedly emphasises the need to “level up outcomes” and reduce unjustified variation in care. PGx testing can play a role in reducing ineffective or harmful prescribing for conditions that disproportionately affect deprived or minority communities — supporting a more equitable healthcare system.
Innovation That Supports a Sustainable NHS
A major focus of the plan is building a “productive and financially sustainable NHS.” Pharmacogenomics contributes to this by:
Reducing avoidable hospital admissions
Minimising treatment failures
Freeing up capacity in overburdened systems
By streamlining prescribing pathways, PGx supports the kind of efficient, modern care model the plan envisions.
What’s Needed to Make It Happen?
To embed pharmacogenomics into the fabric of the NHS, we’ll need:
Investment in clinician education and PGx training
Scalable infrastructure for genetic testing
Clear clinical guidelines and integration into care pathways
As the plan puts it, "the NHS must be ready to take full advantage of emerging technologies" — and pharmacogenomics is a prime example.
Mantara's Role in the Future of Personalised Care
At Mantara, we’re proud to support the NHS’s shift towards smarter, more personalised medicine. We work with healthcare professionals across disciplines to incorporate PGx into daily practice and improve patient outcomes.
If you'd like to learn more about how PGx can help you deliver on the NHS’s vision for personalised, efficient, and equitable care, get in touch with us here.